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Mind

Alice in Wonderland syndrome mapped in the brain to improve treatments

Scientists have mapped the brain circuit behind a form of Alice in Wonderland syndrome, when someone sees themselves or others in distorted proportions, in research that could improve how it is treated

By Kena Shah

31 January 2024

Alice grows out of the room, illustrated by Sir John Tenniel for the first edition of Lewis Carroll's "Alice's Adventures in Wonderland"

Alice grows out of the room, illustrated by John Tenniel for the first edition of Lewis Carroll’s Alice’s Adventures in Wonderland

The Granger Collection/Alamy Stock Photo

People with a form of the rare and somewhat mysterious Alice in Wonderland syndrome may one day have better diagnostic and treatment options after scientists mapped a circuit in the brain implemented in the condition.

Named after Lewis Carroll’s eponymous character, Alice in Wonderland syndrome (AIWS) describes people seeing or perceiving their own body parts – as well as those of others, and objects – in distorted proportions, such as…

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